1. Obesity related complications in children and adolescents
27% exhibit dyslipidemia (Appendix 1.1)
31% exhibit liver and 66% exhibit muscle steatosis (Appendix 1.2, Appendix 1.3, Appendix 1.4, and Appendix 1.5)
50% exhibit pre- or overt hypertension (Appendix 1.6 and Appendix 1.7)
10,4% exhibit subclinical hypothyroidism (Appendix 1.8)
16,5% exhibit vitamin D deficiency (Appendix 1.9)
44 % exhibit sleep apnea (Appendix 1.10)
2. Treatment in the primary sector with the following effects:
74% of patients exhibit weight loss (Appendix 2.1)
Improvement of quality of life (Appendix 2.2)
Reduction in blood pressure (Appendix 2.3)
Reducing obesity and increasing quality of life, physical activity, mood, body perception and reducing appetite and bullying with the digital solution DrHolmApp (Appendix 2.4)
3. Treatment in the secondary sector with the following effects:
69% and 75% exhibit weight loss (Appendix 3.1 and Appendix 3.2)
Reduction in cholesterol levels (Appendix 3.3)
Reduction in blood pressure (Appendix 3.4 and Appendix 3.5)
Reduction of fatty liver and muscle fat (Appendix 3.6)
Improvement of quality of life (Appendix 3.7)
Weight loss in parents (Appendix 3.8)
Improvements in 9 out of 10 in cholesterol levels/degree of obesity/body composition (Appendix 3.9)
Equally effective treatment response despite familiar predispositions to obesity related comorbidities (Appendix 3.10)
Equally effective treatment response despite impaired glucose metabolism (Appendix 3.11)
Equally effective treatment response despite a genetic risk score composed of 15 commonly occurring with impact on development of obesity in children and youth (Appendix 3.12)
Same obesity treatment aproach regardless of disturbed eating behavior (Appendix 3.13)
Reduction of sleep apnea (Appendix 3.14)
Reducing obesity and increasing quality of life, physical activity, mood, body perception and reducing appetite and bullying with the digital solution DrHolmApp (Appendix 3.15)
Danish recommendations based on this method (Appendix 3A)
International recommendations for the treatment of youth with obesity (Appendix 3B)
4. Medication to children and adolescents with obesity
Patients with MC4R mutations are more difficult to treat (Appendix 4.1)
Patients with MC4R mutations (heterozygous) can be treated with medicine (Appendix 4.2)
Inconsistencies in dosage of medication in children and youth with obesity (Appendix 4.3)
Patients with MC4R mutations (homozygous) can be treated with medicine (Appendix 4.4)